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Collaborations with Life Sciences companies and academic organisations are
a central component of our business strategy.
Collaborations with life sciences companies
AlgoNomics initiated several collaborations regarding vaccine development,
therapeutic peptide discovery and the Immunoprofiling of therapeutic proteins.
These collaborations include:

- 4-Antibody AG: 4-Antibody AG has access to Epibase® technology for T-cell epitope identification.

- Ablynx NV: Ablynx and AlgoNomics have a research collaboration
regarding the selection of antibody derived peptide leads.

- Alligator Bioscience: Alligator Bioscience AB addresses immunogenicity with Epibase® to maximally reduce immunogenicity upon optimization of protein therapeutics with Alligator's proprietary ssDNA recombination technology FIND®.

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BAC: BAC bv has access to AlgoNomics’ structural bioinformatics platform.

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Bayer Cropscience: AlgoNomics has entered into a research
collaboration with Bayer Cropscience involving protein engineering and enzyme
substrate modification.

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Bayer HealthCare: Bayer HealthCare AG has access to Epibase® technology for T-cell epitope profiling.

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CAT: Cambridge Antibody Technology Ltd. has access to Epibase® Technology for T-cell epitope profiling.

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Crucell: Crucell Ltd. has access to Epibase® Technology for T-cell epitope profiling.

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Centocor: Centocor, member of the Johnson & Johnson family of companies, has access to Epibase® Technology for T-cell epitope profiling.

- Evogenix Ltd.: Evogenix Ltd. has access to Epibase® Technology for T-cell epitope identification.

- Evolutec Ltd.: Evolutec Ltd. has access to Epibase® Technology for T-cell epitope identification.

- Genmab AS: AlgoNomics NV entered into an agreement granting
Genmab A/S access to the Epibase® platform for T-cell epitope identification.

- GSK Biologicals: GSK Biologicals has access to Epibase® Technology for T-cell epitope identification.
- GSK R&D: GSK Research and Development has access to Epibase® Technology for T-cell epitope identification.

- Innogenetics NV: Innogenetics employs the Epibase®
platform in the development of an Hepatitis C poly-epitope vaccine.

- Kirin Brewery: Kirin Brewery Ltd. has access to Epibase® technology for the immunoprofiling of
therapeutic proteins.

- MAT Biopharma: MAT Biopharma SA and AlgoNomics entered into a research collaboration.
AlgoNomics will employ its structural bioinformatics platform to assist MAT Biopharma
in its research related to the structural analysis of its antibody leads

- Maxygen: Maxygen Inc. has access to Epibase® Technology for T-cell epitope identification.

- Pepscan Systems BV: Pepscan Systems announced positive
results in the rational design of antibody binding peptides using our Tripole
technology.
The companies intend to exploit their “peptide-design-cycle” platform
in the vaccination field.

- Peptech Ltd.: Peptech has access to Epibase® Technology for T-cell epitope identification.

- Pevion Biotech Ltd.: Pevion Biotech and AlgoNomics collaborate
to rationally design RSV-derived peptides for use in vaccines.

- Pieirs AG: Pieris has access to Epibase® Technology for T-cell epitope identification.

- ProtAffin Biotechnologie AG: ProtAffin Biotechnologie has access to Epibase® Technology for T-cell epitope identification.

- Resistentia Pharmaceuticals AB: Resistentia Pharmaceuticals has access to Epibase® Technology for T-cell epitope identification.

- Syntaxin Ltd: Syntaxin has access to Epibase® Technology for T-cell epitope identification.

- Tibotec: AlgoNomics entered into a research collaboration
with Tibotec, a subsidary of Johnson & Johnson, involving structural bioinformatics
services on undisclosed targets.
 
- UCB Celltech: UCB Celltech has access to Epibase® Technology for T-cell epitope identification.

- Viragen: Viragen has access to Epibase® Technology for T-cell epitope identification.
Collaborations with academic groups
Academic collaborations were initiated with:
- Academic Medical Center (Amsterdam, NL)
- Institute of Tropical Medicine (Antwerp, BE)
- Laboratoire de retrovirologie (Luxembourg, LU)
- Leiden University Medical Centre LUMC (Leiden, NL)
- Medical Research Council (Cambridge, UK)
- Rega Institute (Leuven, BE)
- Université de Liége (Liége, BE)
- University of Texas (TX, USA)
- Vrije Universiteit Brussel (Brussels, BE)
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