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Van Walle I, Gansemans Y, Parren P, Stas Ph, Lasters L.
Immunogenicity screening in protein drug development
Expert Opinion on Biological Therapy (2007) 7(3):405-18

Fontayne A, Vanhoorelbeke K, Pareyn I, Van Rompaey I, Meiring M, Lamprecht S, Roodt J, Desmet J, Deckmyn H.
Rational humanization of the powerful antithrombotic anti-GPIbalpha antibody: 6B4
Journal of thrombosis and haemostasis (2006) 96(5):671-84

Staelens S, Desmet J, Ngo T, Vauterin S, Pareyn I, Barbeaux P, Van Rompaey I, Stassen J, Deckmyn H, Vanhorelbeke K.
Humanization by variable domain resurfacing and grafting on a human IgG4, using a new approach for determination of non-human like surface accessible framework residues based on homology modelling of variable domains.
Molecular Immunology (2006) 43(8):1243-57

Desmet J, Meersseman G, Boutonnet N, Pletinckx J, De Clercq K, Debulpaep M, Braeckman T, Lasters I.
Anchor profiles of HLA-specific peptides: analysis by a novel affinity scoring method and experimental validation.
Proteins (2005) 58(1):53-69

Ivo Van Walle, Ignace Lasters, and Lode Wyns.
Align-m–a new algorithm for multiple alignment of highly divergent sequences.
Bioinformatics (2004), 20(9):1428–35

Van Walle I., Lasters I. & Wyns L.
Consistency Matrices: Quantified Structure Alignments for Sets of Related Proteins
Proteins (2003) 51,1–9

Boutonnet N., Janssens W., Boutton C.,Verschelde JL., Heyndrickx L., Beirnaert E., van der Groen G. & Lasters I.
Comparison of Predicted Scaffold-Compatible Sequence Variation in the Triple-Hairpin Structure of Human Immunodeficiency Virus Type 1 gp41 with Patient Data.
J Virol. (2002) 76(15):7595-606

Desmet J, Spriet J & Lasters I.
Fast and accurate side-chain topology and energy refinement (FASTER) as a new method for protein structure optimization.
Proteins (2002) 48(1), 31-43

van den Beucken T., van Neer N., Sablon E., Desmet J., Celis L., Hoogenboom HR & Hufton SE.
Building novel binding ligands to B7.1 and B7.2 based on human antibody single variable light chain domains.
J Mol Biol. (2001) 310(3), 591-601

Boutonnet N., Van Belle D. & Wodak S.
Infuence of ligand binding on the conformation of Ligand of Torpedo
Acetylcholinesterase.

Theor. Chem. Acc. (2001) 106, 10-21.

Desmet J., De Maeyer M., Spriet J.& Lasters I.
Flexible docking of peptide ligands to proteins.
Methods Mol Biol. (2000) 143, 359-76

De Maeyer M., Desmet J.& Lasters I.
The dead-end elimination theorem: mathematical aspects, implementation, optimizations, evaluation, and performance.
Methods Mol Biol. (2000) 143, 265-304.

Hufton SE., van Neer N., van den Beucken T., Desmet J., Sablon E.& Hoogenboom HR..
Development and application of cytotoxic T lymphocyte-associated antigen 4 as a protein scaffold for the generation of novel binding ligands.
FEBS Lett. (2000) 475(3), 225-231.

Boutonnet N., Kajava A. & Rooman M.
Structural classification of a and b supersecondary structure units in proteins.
Proteins (1998) 30, 193-212.

Desmet, J., Wilson, I.A., Joniau, M., De Maeyer, M. & Lasters, I.
Computation of the binding of fully flexible peptides to proteins with flexible side-chains.
The FASEB J. (1997) 11, 164-172.

De Maeyer, M.., Desmet, J., & Lasters, I.
All in one: a highly detailed rotamer library improves both accuracy and speed in the modeling of side-chains by dead-end elimination.
Folding & Design (1997) 2, 53-66.

Lasters, I.., Desmet, J. & De Maeyer, M..
Dead-end based modeling tools to explore the sequence space that is compatible with a given scaffold.
J. Protein Chem. (1997) 16, 449-452.

Desmet, J., De Maeyer, M.. & Lasters, I.
Theoretical and algorithmical optimization of the Dead-End Elimination theorem.
in 'Proceedings of the Pacific Symposium on Biocomputing 1997' (1997) Altman, R.B., Dunker, A.K., Hunter, L. & Klein, T.E. (eds.) World Scientific, Singapore, pp. 122-133.

Lasters, I.., De Maeyer, M.. & Desmet, J.
Enhanced Dead-End Elimination in the search for the global minimum-energy conformation of a collection of proteins side-chains.
Protein Eng. (1995) 8, 815-822.

Boutonnet N., Rooman M. & Wodak S.
Automatic analysis of protein conformational changes of by multiple linkage clustering.
J. Mol. Biol. (1995) 253(4), 633-647.

Boutonnet N., Rooman M., Ochagavia M.E., Richelle J. & Wodak S.
Optimal protein structure alignments by multiple linkage clustering: application to distantly related proteins.
Protein Eng. (1995) 8(7), 647-662.

Desmet, J., De Maeyer, M.. & Lasters, I..
The 'Dead End Elimination' Theorem as a New Approach to the side-chain Packing Problem.
in 'The Protein Folding Problem and Tertiary Structure Prediction' (1994) Merz, K. & LeGrand, S. (eds.) Birkhäuser Boston, Inc., pp. 307-337.

Lasters, I.. & Desmet, J.
The fuzzy-end elimination theorem: correctly implementing the side-chain placement algorithm based on the dead-end elimination theorem.
Protein Eng. (1993) 6, 717-722.

Desmet, J., De Maeyer, M.., Hazes, B. & Lasters, I..
The Dead End Elimination Theorem and its use in protein side-chain positioning.
Nature (1992) 356, 539-542.

 
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